Recent medical literature has revealed an alarming side effect of GLP-1 (glucagon-like peptide 1) receptor agonists. GLP-1s drugs are used to aid in weight loss. They work by decreasing the activity of the digestive system and the body’s reward system (users report fewer cravings for food as well as pleasurable activity).
One study reporting on the hair loss side effect of GLP-1 drugs found that the degree of hair loss was dependent on the strength of the medication and the dose. The stronger the drug and higher the dose, the greater the hair loss.[i] This means that GLP-1s are likely causing hair loss.
Hair loss caused by GLP-1 use seems to fall into 1 of 2 categories.
- Androgenetic alopecia – this is hair loss that occurs in a particular pattern. In women it takes shape in a “Christmas tree” distribution and for men it affects the front and temples.
- Telogen effluvium – this is hair loss that occurs all over the scalp. The typical description of this condition is “hair falling out in clumps” and typically occurs after highly stressful life events such as deaths in the family, surgeries, or hospitalizations. Interestingly the previously mentioned study noted that rapid weight loss was associated with telogen effluvium. TE is typically passes with time.
It is not certain but probable that hair loss caused by GLP-1 receptor agonists is reversible upon stopping the medication.
DHT Blockers may help with androgenetic alopecia caused by GLP-1 receptor agonists. Ingredients that support hair growth such as biotin may support hair growth once telogen effluvium passes.